Monday, April 6, 2020
20 Topics for a Domestic Violence Research Paper to Discuss the XXI Century Problems
20 Topics for a Domestic Violence Research Paper to Discuss the XXI Century Problems When a professor assigns you a paper to write, you might be given the option to choose what you want to write about. Other professors will give you a broad topic, such as domestic violence. This means that you can choose a smaller category within the overarching topic. This is easier said than done. Deciding on an essay topic can be one of the hardest parts of the entire essay writing process. You have to make sure that your idea has plenty of research and information that you can include in your paper. A strong topic with good evidence makes for an easy research paper. If you need to write a research paper on a topic related to domestic violence, take a look at these topic ideas: What Role Does Todayââ¬â¢s Economic Situation Play in Domestic Violence? Recent Efforts in Domestic Violence Prevention Plans Why Is Intimate Partner Violence Currently One of the Leading Causes of Domestic Violence? Domestic Violence in Same-Sex Relationships How Are Family Members Affected by Intimate Partner Violence? How Have Government Solutions for Domestic Violence Improved Over the Past Decade? The Connection Between Economic Abuse and Domestic Abuse Long-Term Effects of Domestic Violence on Millennial Victims What Types of Technology Are Available for Noticing and Reporting Domestic Violence Situations? Negative Impacts on Children Who Witness Domestic Violence in Their Homes or in Movies Up-and-Coming Treatment Options for Domestic Violence Victims What Kind of Role Does Social Media Play in Domestic Violence? How Does the New Rise of Feminism Help or Hinder Domestic Violence Progress? Is the Stigma of Men Being Abusers in Domestic Violence Situations Changing? How Does Violence in Current Films Influence Domestic Violence Statistics Today? Are Current Laws Against Domestic Violence Being Enforced? What Needs to Be Changed for Better Regulation? Is There a Connection Between Domestic Violence and Violent Video Games? New App Development for Domestic Violence Rescue Situations Current Domestic Violence Statistics and Treatment Options Around the World What Is the Current Correlation Between Domestic Violence and Social Status? Those are some of the best topics that you can use for a domestic violence research paper. You can choose just one or combine a couple of the ideas to create your own topic. These themes can spark new ones as well. Maybe they highlight an area you hadnââ¬â¢t considered exploring! To get more ideas to disclose in your paper, have a look at 10 facts about domestic violence that could come in handy to hook the audience. Sample Essay: Domestic Violence in Same-Sex Relationships With same-sex relationships and marriages on the rise, some questions have arisen, especially relating to the structure and roles within the relationship. People on the outside often wonder which heterosexual relationship challenges occur in same-sex relationships. This uncertainty can sometimes lead to confusion and misconceptions, specifically in domestic violence situations. Though it may seem as if domestic violence only occurs in heterosexual relationships, it is just as prevalent in same-sex relationships in various ways and for several different reasons. Firstly, it is necessary to realize that every relationship, regardless of its members, has a different structure. These various roles can influence who might be in control in a relationship or how responsibilities are distributed. These factors apply to couples of all types. Because of this, a power struggle can always become a possibility and may result in domestic violence. Often, the control continues to rule over the relationships. In these situations, the victim feels trapped and cannot safely escape from a threatening relationship. The control can be too much for the victim to handle, or they might feel like they cannot speak up about their lack of voice in the situation. This is true no matter the partners are of the same sex or not. Secondly, same-sex couples are the subject to all of the same challenges as heterosexual couples. There are family problems, work issues, personal struggles, and more. Certain relationship types do not protect people from these natural difficulties. One major contributor to domestic violence and abusive situations is often an economic status. Again, it is important to note that this can happen to any person or couple, regardless of any other demographics. Financial and economic issues lead to tension and arguments in some cases. This can, then, progress to violence. These events usually arise in lower-income homes, but that is not always true. While low-income homes are more susceptible to domestic violence, there are still plenty of well-off couples who experience violence within their marriage or relationship. Having enough money and resources is not protection against abuse. Thirdly, it is critical to mention that there are fewer abuse treatment options available for those in same-sex relationships. Homosexual individuals are not necessarily excluded in these places, but there is no clear mention of them being welcome. This can also be true of male domestic violence victims. Most of the time, treatment is geared toward women who are leaving abusive situations. Because of this, homosexuals of all types, and men as well, can feel excluded. There is a stigma surrounding domestic violence that pairs getting help with weakness. In general, this is one of a few things that keeps men from seeking out help. This can appear in homosexual partnerships too. Additionally, it is important to consider who the abuser is in same-sex partnerships. There should be equal treatment opportunities for all people, regardless of their gender or their place in a relationship. Sometimes, if a female is abusing someone, there will be little to no sympathy. This also contributes to the action taken on the issue. In lesbian relationships, bouts of domestic violence might be seen as a catfight. This misinterpretation of the potential violence leads to unresolved problems. A woman is doing the abusing does not delegitimize the entire act of violence. In conclusion, there are more than a few important aspects of violence to consider specifically in the same-sex relationships. Most of these issues arise in heterosexual relationships as well, but they are not often recognized in the same way. This can be displayed through fewer treatment opportunities or issues that involve victims being taken less seriously. These include things like power struggles and gender roles that are present in all types of relationships. References: Estes, M. L., Webber, G. R. (2017). ââ¬Å"More Closeted Than Gayness Itselfâ⬠: The Depiction of Same-Sex Couple Violence in Newspaper Media. Journal of Interpersonal Violence, 088626051773627. doi:10.1177/0886260517736271 Hamilton, G. (n.d.). Current Issues in Domestic Violence. Retrieved March 23, 2018, from https://www.calsouthern.edu/content/articles/psychology-articles/current-issues-in-domestic-violence Pearlman, D. N. (2003). Neighborhood Environment, Racial Position, and Risk of Police-Reported Domestic Violence: A Contextual Analysis. Public Health Reports, 118(1), 44-58. doi:10.1093/phr/118.1.44 Renzetti, C. M., Miley, C. H. (2014). Violence in gay and lesbian domestic partnerships. London: Routledge. Savage, C. (2010, June 10). Gay Couples Gain Under Violence Against Women Act. Retrieved March 23, 2018, from https://www.nytimes.com/2010/06/11/us/politics/11gender.html Stiles-Shields, C., Carroll, R. A. (2014). Same-Sex Domestic Violence: Prevalence, Unique Aspects, and Clinical Implications. Journal of Sex Marital Therapy, 41(6), 636-648. doi:10.1080/0092623x.2014.958792 Wasarhaley, N. E., Lynch, K. R., Golding, J. M., Renzetti, C. M. (2016). The Impact of Gender Stereotypes on Legal Perceptions of Lesbian Intimate Partner Violence. Journal of Interpersonal Violence, 32(5), 635-658. doi:10.1177/0886260515586370
Monday, March 9, 2020
Using the Spanish Verb Deber
Using the Spanish Verb Deber The Spanish verb deber is quite common and can be used to express obligation or that something that is likely.à Key Takeaways: Using the Spanish Verb 'Deber' The everyday verb deber is most often used to express that someone has a debt or is obligated to do something.The phrase deber de can be used to indicate that something is highly probable.In the preterite, deber is used to indicate that something should have been done. Expressing Obligation When used in this way, deber is frequently similar in meaning to the English must, should, or ought: Debes estudiar tus lecciones. (You ought to study your lessons.)à ¿Quà © carro debo comprar? (Which car should I buy?)Alguien deber hablar de todo esto. (Someone will have to talk about all this.)No debe dormirse despuà ©s de comer. (He shouldnt go to sleep after eating.) The tone of deber to express obligation can be softened by using the conditional form instead of the present tense, although the difference isnt always translatable. When telling someone what he or she should be doing, using the conditional can come across as more polite: No deberà as abrir un blog si vas a hablar de temas personales. (You shouldnt start a blog if youre going to talk about personal subjects.)La Fuerza Aerea deberà a comprar mejores aviones de combate. (The Air Force should buy better combat planes.)Hay 25 libros que deberà amos leer antes de cumplir los 30. (There are 25 books we should read before we reach our 30s.) Expressing a Debt When used with a noun direct object, deber can usually be translated as owe. No me debes nada. (You dont owe me anything.)El gobierno le debe ms de $3 millones a mi madre. (The government owes my mother more than $3 million.)Siempre te voy a deber el haberme levantado cuando tan abajo estaba. (I am always going to owe you for having lifted me up when I was so low.) Expressing Strong Probability The phrase debes de is used to refer to a strong likelihood. In such cases, it is often the equivalent of the English must when must isnt used to express obligation: No debiste de firmar nada. (You must not have signed anything.)Debo de ser anormal. (I must be abnormal.)Deben de estar en buena condicià ³n. (In all likelihood, they are in good condition.) It is very common in some areas, especially in speech, to drop the de in sentences such as those above. However, out of context, doing so would make the sentences ambiguous. Thus while ââ¬â¹debà as de verme can mean only you must have seen me, debà as verme can mean either you must have seen me or you ought to have seen me. In that case, you would need to know the context to understand what was meant. On occasion, in some regions, you may hear deber de to express obligation. However, this usage is frowned upon by grammarians and should not be imitated if you are learning the language. Using Deber in the Preterite In the preterite tense, the rough equivalent of the simple past tense in English, deber can be used to indicate that something should have been done. Son las palabras que no debiste decir. (They are the words you shouldnt have said.)Pedro debià ³ pedir disculpas a sus empleados tras la difusià ³n del video. (Pedro should have asked for forgiveness from his employees after the video was broadcast.)Debà ver que esto iba a ocurrir. (I should have seen that this was going to happen.) Phrases Using Deber These are among the common phrases using deber: Deberse a (owing to, due to): El aumento de las enfermedades crà ³nicas se debe a nuestro estilo de vida. (The increase in chronic illness is due to our lifestyle.)Cumplir con su deber (to do or fulfill ones duty): Complà con mi deber de votar. (I fulfilled my duty to vote.)No deberse a nadie (to be answerable to nobody): El presidente no se debe a nadie - salvo a todos los ciudadanos de todos y cada uno de los estados. (The president isnt answerable to anyone - except for all the citizens of each and every one of the states.)Sentido del deber (sense of duty): No puedes decir que me falta el sentido del deber. (You cant say I lack a sense of duty.)
Friday, February 21, 2020
Is War Against Terrorism Moral And Has It Done Things Better Or Worse Essay
Is War Against Terrorism Moral And Has It Done Things Better Or Worse - Essay Example This essay stresses that the Christians the world over were in a state of bother and tension so as to find out the real reason why the world had stood up against them and were hell bent upon destroying them. It would not be wrong to state at this point that Christians all over the world were vocal and carried out large processions as to encourage the US government and its allies to take steps to counter these very attacks. A number of wars and fights started in the wake of War on Terrorism and it sparked off a number of controversies as to the real reasons for starting the same on countries like Afghanistan and Iraq. This paper makes a conclusion that the war on terror has brought a change in the way the world is being run. The different governments have to take one or the other side in this whole muddle. The need is to understand who the winner is and who the loser is eventually. More than that, the governments have to seek ways in which they could counter the pressures that are exerted by the US regime from time to time. For third world nations, this becomes an issue of immense importance since they are already stuck in one problem or the other, add to that the pressure meted down by the US authorities every now and so often. War on terror is not a war on the poor yet oil rich nations, it is a war for the benefits of the super power of the world, which it wants to win no matter what happens.
Wednesday, February 5, 2020
Ethics and special need kids Research Proposal Example | Topics and Well Written Essays - 3000 words
Ethics and special need kids - Research Proposal Example On the other hand, the same case applies to the perception of African American teachers towards white students and the course is the same. According to Oates (2003), positive disposition of teachers towards students tends to yield good results on the performance of the students. However, in the history of the U.S, there has been a notion that the African Americans have academic inferiority and that they lack diligence to perform. In another dimension, such notions have rendered the African Americans a low self esteem motive that makes them have a negative attitude about themselves in regard to their academic performance. Generally, although the African American students have equal opportunities in classroom in public schools, their performance is greatly affected by the context of their race and teachersââ¬â¢ perception (Oates, 2003). Conversely, the general place of African Americans in the American society also plays a critical role in explaining why the students cannot perform well in class. For instance, the perception that African Americans cannot secure good jobs in the U.S greatly affect their class performance because there is no guarantee that even after completing their studies they would get employed. Focusing on kids with special needs, it is apparent that the issue of racial discrimination fuels. ... In this regard, the perception of teachers towards African American kids with special needs is that their parents are incapable of taking care of the kids and that is why they are in their current conditions. For instance, a kid who cannot afford three daily meals tends to lack capacity to contemplate what they are taught in class. Mostly, such a kid comes from African American families. In another dimension, the perception by teachers that African American kids cannot perform better than the white kids has also played a key role on the continued underperformance by the kids. In light of this, teachers tend to focus most of their attention to white kids. A study conducted by Neal, et al (2003), found out that white kids are accorded much attention that African American students. For instance, teachers concentrate on areas they did not understand more compared to when it is the African American kids that raise the issue of lack of contemplation. Dee (2006) pointed out that, teachers p erceptions independently affect and influence academic performance via self-fulfilling beliefs and perceptual biases. In addition, if teachers are pleasant towards a certain student, they provide them with more effective and favorable instructions. The same case applies to situations where pleasant students portray poor problem solving skills, teachers guide them in a way that easily encourage them to develop good solving skills. This is centrally to situations where unpleasant students portray the same skills, teachers put little effort to encourage or correct them. In fact, Gay (2002) postulated that performance of students is in the mind of the teacher. They tend to evaluate students performance based on their perception about the students. In light of this, it is
Tuesday, January 28, 2020
Research on Immunology in Pregnancy
Research on Immunology in Pregnancy Investigative Review Nichole Gale The systems controlling the implantation and acceptance of the genetically and immunologically foreign fetus within the maternal body have often been likened to that of an organ transplant, or the growth of a cancerous tumour. The fetus is ââ¬Ëlike a transplanted kidneyââ¬â¢, in the way that it is ââ¬Ëgenetically different from the hostââ¬â¢ and ââ¬Ëmust evade immune defences to avoid rejectionââ¬â¢ (Quinn 1999). The fetus inherits ââ¬Ëforeign paternally derived histocompatibility genesââ¬â¢, meaning that ââ¬Ëthere is close contact between two genetically disparate individualsââ¬â¢ within the maternal body (Warshaw 1983, p63). Thus, the fetus is often referred to as an allograft, an allograft being a ââ¬Ëgraft transplanted by an individual that is not genetically identical, but of the same speciesââ¬â¢ (Marieb 1998, p789). The subject of fetus acceptance and tolerance within the maternal body has triggered great interest and controversy, and the sy stems that allow the acceptance of the fetus are complex and varying. Internal gestation has involved ââ¬Ëa wide range of adaptations of animals for retention of young within the body of the parentââ¬â¢ (Warshaw 1983, p63). The human immune system includes many ââ¬Ëcellular patterns that constantly exchange informationââ¬â¢ to provide the body with the ability to ââ¬Ërecognise foreignness or ââ¬Å"non-selfâ⬠in the form of antigens that enter our bodyââ¬â¢ (Warshaw 1983, p200). The recognition of antigens spark the inflammatory response, which must act with ââ¬Ëminimum damage to the hostââ¬â¢, in order to ââ¬Ëeliminate the intruderââ¬â¢ (Warshaw 1983, p200). ââ¬ËAntigens are expressed by early human embryonic tissueââ¬â¢ (Loke 1978, p5), so it could be expected that the early human embryo would trigger an inflammatory response to rid the motherââ¬â¢s body of the ââ¬Ëforeign bodyââ¬â¢. The exposure to non-self paternal antigens on the fetus ââ¬Ërequires the adaptation of the maternal immune system to prevent the rejection of the allogeneic fetus without compromising the ability of the mother to fend off infectionââ¬â¢ (Koch Platt 2003). The immune system consists of an innate (humoral) and an adaptive (cellular) component, in order to combat potential pathogens. It has been suggested that the main immune response triggered by the fetus is the adaptive response, where there is antigen representation, followed by response instruction by Helper T cells (Quinn 1999). In normal pregnancy, progesterone suppresses the humoral response. This has been used to explain why some autoimmune diseases, such as rheumatoid arthritis that are under humoral effect, often improve during pregnancy (Quinn 1999). Early work on immunological tolerance, conducted by Medawar, has been the foundation of further studies regarding the paradox of pregnancy. Medawar proposed three mechanisms that might together act to allow immune protection of the fetus. Two of Medawarââ¬â¢s earlier suggested mechanisms have since been proved to not actually ââ¬Ëpertain during pregnancyââ¬â¢ (Aluvihare, Kallikourdis Betz 2004). The first hypothesis was that there was ââ¬Ësegregation of the fetal and maternal circulationsââ¬â¢, or that ââ¬Ëa barrier might form between the mother and fetus, preventing exposure of the maternal immune system to allogeneic antigens expressed on fetal tissueââ¬â¢, leading to immunological ignorance (Koch Platt 2003). Medwarââ¬â¢s second hypothesis referred to the immunological immaturity of fetal tissue, and this allogenic immaturity acting to suppress the ââ¬Ëexpression of antigens that the maternal immune system might recognise as foreign and target for dest ructionââ¬â¢ (Koch Platt 2003). More recent research has tended to focus on Medwarââ¬â¢s third hypothesis, ââ¬Ëthat the maternal immune system somehow ignores potentially immunogenic fetal tissueââ¬â¢ (Aluvihare, Kallikourdis Betz 2004). Leading from this, there has also been much focus on ââ¬Ëthe means of inducing immune tolerance, the emergence of T cell suppression in mediating peripheral tolerance, the mechanisms mediating matererno-fetal tolerance and the role played by regulatory T cells in mouse and human pregnancyââ¬â¢ (Aluvihare, Kallikourdis Betz 2005). Koch and Platt (2003) suggest overlapping mechanisms such as ââ¬Ëthe formation of an anatomical barrier between mother and fetus, lack of maternal immune responsiveness, and a lack of expression of allogenic molecules by the fetusââ¬â¢ to account for the lack of fetal rejection. These mechanisms can help in beginning to understand how rejection is avoided, yet do not ââ¬Ëcompletely explain how the fetus evades the maternal immune systemââ¬â¢ (Koch Platt 2003). Harding and Bocking (2001, p238) state that it was originally proposed that the maternal-fetal interface was perhaps ââ¬Ëan immunologically privileged siteââ¬â¢, or that there was a ââ¬Ëgeneralised suppression of maternal immune responseââ¬â¢. Recent studies have challenged earlier theories such as these, and it has since been found that not only is there actual recognition of fetal alloantigens by the motherââ¬â¢s immune system, but that her body also responds to them. Fetal cells can be detected in maternal circulation, and ââ¬Ëfetal tissue expresses MHC class I and class II and is antigenically matureââ¬â¢ (Aluvihare, Kallikourdis Betz 2004). MHC are major histocompatibility complex proteins coded for by genes. Class I are found on virtually all body cells, whereas class II displayed only by cells that act in immune response (Marieb 1998). The understanding of the immune events and mechanisms occurring at the maternal-fetal interface are likely to help in the understanding of the ability of the fetus to survive within the maternal body. Since Medawarââ¬â¢s proposed hypotheses, much focus has continued on fetal immune evasion mechanisms. As well as the three mechanisms above, suggested by Medawar, Koch and Platt (2003) explore a fourth mechanism, site-specific suppression. This refers to ââ¬Ëlocal suppression of maternal immune responses at the maternal-fetal interfaceââ¬â¢ (Koch Platt 2003). ââ¬ËLocalised suppression at the maternal-fetal interface during pregnancy negates the need for systemic immunosuppression which could threaten the well-being of the motherââ¬â¢ (Koch Platt 2003). Earlier studies suggested that trophoblast acted simply as a barrier between the mother and fetus, but it now seems that perhaps that it could have ââ¬Ëdiverse immunoregulatory properties controlling immune recognition, activation, and effector functionsââ¬â¢ (Koch Platt 2003). It has been proposed by various studies that T cells play a major role in sustaining pregnancy. T cells are lymphocytes that mediate cellular immunity. ââ¬ËT cells with regulatory functions are potent suppressors of T cell responses and can protect tissues from T cell mediated destructionââ¬â¢ (Mellor Munn 2004). Observations in experimental pregnant mice have shown that while pregnant, they tend to ââ¬Ëoverproduce a kind of T cell that reins in other immune cells that might target the fetusââ¬â¢ (Seppa 2004). In one study, conducted by immunologist Betz (Seppa 2004) it was found that ââ¬Ëpregnant mice have double to triple the number of CD4+ CD25+ T cells, also called regulatory T cells, in their blood, spleen, and lymph tissue as do female mice that are not pregnantââ¬â¢. It has also been shown that in humans, levels of circulating CD4+ and CD25+ cells ââ¬Ëincreases progressively at each stage in human pregnancy starting from the first trimesterââ¬â¢ (Mello r Munn 2004). It has been ââ¬Ëdemonstrated that Tregs (T regulator cells) have a key role in regulating maternal effector T cell responses to fetal alloantigensââ¬â¢ as maternal effector T cells seem to ââ¬Ëpose a potentially lethal threat to the developing fetus in the absence of regulatory function mediated by maternal Tregsââ¬â¢ (Mellor Munn 2004). It has also been speculated ââ¬Ëthat hormonal changes during pregnancy might provide one explanation for enhanced maternal Treg development during fetal gestation because pregnancy-associated hormones, such as progesterones, promote immunosuppressionââ¬â¢ (Mellor Munn 2004). In regard to the suppression of maternal immunity, it is still ââ¬Ëunclear if Tregs directly or indirectly inhibit effector T cell responses to fetal alloantigensââ¬â¢ (Mellor Munn 2004). To further test the cellsââ¬â¢ effect on pregnancy, 30 female mice were mated with males. 15 out of the 30 mice had fully functioning immune systems, whilst the other 15 mice lacked the regulatory T cells. While a slightly higher than normal number of healthy female mice became pregnant, none of the mice lacking T cells were able to become pregnant. It seems that the role of T cells remains unclear, but that further understanding ââ¬Ëof the role of regulatory T cells might also lead to new treatments for suppressing rejection of transplanted organs and inhibiting autoimmune reactions, in which a persons immune cells attack his or her own tissuesââ¬â¢ (Seppa 2004). Mellor and Munn (2004) also suggest that the revelation that ââ¬Ëmaternal Tregs might help protect the developing fetusââ¬â¢ will have various implications, not only the possibility of offering alternative therapies to suppress immunity, but also possibilities for ââ¬Ëimproving pregnancy success rates in p atients with problematic pregnanciesââ¬â¢. Again, the effect of T cells on autoimmune diseases is referred to by Mellor and Munn (2004), ââ¬Ëincreased systemic Treg function might explain why some autoimmune syndromes, such as rheumatoid arthritis, go into remission during pregnancyââ¬â¢. There has also been some discussion on the role of macrophages as immunoregulators of pregnancy. It has been claimed that most attention has focused on immune tolerance to the invading trophoblast and fetus, but Mor and Abrahams (2003) suggest that it is also important to ââ¬Ëconsider the function of the maternal immune system in the promotion of implantation and maintenance of pregnancyââ¬â¢. During implantation, apoptosis is necessary for ââ¬Ëtissue remodelling of the maternal decidua and invasion of the developing embryoââ¬â¢ (Mor Abrahams 2003). It has been sited that apoptosis is active in the ââ¬Ëtrophoblast layer of placentas from uncomplicated pregnancies throughout gestation, suggesting that there is a constant cell turnover at the site of implantation necessary for the appropriate growth and function of the placentaââ¬â¢ (Mor Abrahams 2003). During implantation and invasion, it appears that a large number of macrophages are present in the maternal decidu a and in tissues close in proximity to the placenta. Originally it was thought the large numbers of macrophages were ââ¬Ëto represent an immune response against the invading trophoblastââ¬â¢. Mor and Abrahams (2003) propose that this may not be the case, and that ââ¬Ëmacrophage engulfment of apoptotic cells prevents the release of potentially pro-inflammatory and pro-immunogenic intracellular contentsââ¬â¢. Trophoblast cells carry proteins that are antigenically foreign to the maternal immune system. If these proteins are released as a result of cell death, it could initiate or accelerate immunological responses, ââ¬Ëwith lethal consequences for the fetusââ¬â¢ (Mor Abrahams 2003). Therefore, the appropriate removal of the intracellular components by macrophages may be critical for the prevention of fetal rejection. Mor and Abrahams (2003) conclude that the ââ¬Ëfield of apoptotic cell clearance is beginning to flourish, and many questions remain unansweredââ¬â¢. There is not just one mechanism involved in the immune regulation of pregnancy, but ââ¬Ëmultiple, diverse mechanisms that are likely sequential during gestationââ¬â¢ (Koch Platt 2003). As humans have a much longer gestation period, and a more invasive placental anatomy, it is sometimes difficult to test in laboratory animals and apply results to humans, as there may be different mechanisms. But it is believed that mechanisms involved with the fetus can be utilised in the studies of rejection following transplantation. As Koch and Platt (2003) suggest, ââ¬Ëknowledge of the immunoregulatory mechanisms of both the fetus and stem cells will help immunologists understand general mechanisms of tolerance and immune evasion, and will prove invaluable in the fields of organ and cellular transplantationââ¬â¢. It has been suggested that both studies in stem cells and fetal rejection can benefit each other and help in understanding of systems involved. Pregnancy has also been said to have overall effects on the motherââ¬â¢s immune system and maternal defence against organisms. According to Creasy and Resnik (2004, p103) ââ¬Ënumerous reports indicate that pregnant women have increased susceptibility to a variety of infectionsââ¬â¢. It is said that ââ¬Ëthere appears to be a trend toward increased susceptibility to viral infections, consistent with suppressed cell-mediated immunity and a relative decrease in Th1 (humoral/innate) responses during pregnancyââ¬â¢ (Creasy Resnik 2004, p103). However, it also added that ââ¬Ëmore recent carefully analysed data do not indicate that maternal immunity is substantially impaired, and most pregnant women are able to adequately respond to most infectious diseasesââ¬â¢ (Creasy Resnik 2004, p103). Harding and Bocking (2001, p238) also claim that most studies tend to suggest that ââ¬Ëmaternal cell-mediated immunity is unchanged during pregnancyââ¬â¢. According to some experts, infertility, recurrent miscarriage, premature delivery and preeclampsia may all be linked to immunological abnormalities. It could be that some of these problems are due to ââ¬Ëdefective generation of Tregs during pregnancyââ¬â¢ (Mellor Munn 2004). It is possible that methods involving in vitro expansion of Tregs could help in treating spontaneous immune disease syndromes. Koch and Platt (2003) also suggest that both adult and embryonic stem cells might use mechanisms similar to the fetus in avoiding rejection. ââ¬ËFuture discoveries in the field of reproductive immunology will help us understand not only immune regulation during pregnancy, but also how immune responses towards organ and cellular transplants might be controlledââ¬â¢ (Koch Platt 2003). References: Aluvihare, V., Kallikourdis, M., and Betz, A. 2004 ââ¬ËTolerance, suppression and the fetal allograftââ¬â¢. Journal of Molecular Medicine. [Online], vol. 83, no. 2, pp 88-96. Available from: Medline. [11 October 2005]. Creasy R. Resnik R. (ed.) 2004. Maternal-Fetal Medicine, 5th edn., Saunders, Philadelphia. Harding, R., Bocking, A., (ed.) 2001. Fetal Growth and Development, Cambridge University Press, Cambridge. Koch, C. Platt, J. 2003 ââ¬ËNatural Mechanisms for evading graft rejection: the fetus as an allograftââ¬â¢, Springer Seminars in Immunopathology, [Online], vol. 25, no. 2, pp 95-117. Available from SpringerLink. [7 October 2005]. Loke, Y., 1978. Immunology and Immunopathology of the Human Fetal-Maternal Interaction, Elsevier Horth-Holland Biomedical Press, New York. Marieb. E., 1998. Human Anatomy and Physiology, 4th edn., Addison Wesley Longman, California. Mellor, A. Munn, D. 2004 ââ¬ËPolicing pregnancy: Tregs help keep the peaceââ¬â¢, Trends in Immunology. [Online], vol. 25, no.11, pp 563-565. Available from: Medline. [10 October 2005]. Mor, G. Abrahams, V. 2003 ââ¬ËPotential role of macrophages as immunoregulators of pregnancyââ¬â¢, Reproductive Biology and Endocrinology. [Online], vol. 119, no.1. Available from Medline. [11 October 2005]. Quinn, T. (1999), Immunology in Pregnancy; The Fetal Allograft, [Online], SIU Medical Library. Available from: http://www.siumed.edu/lib/ref/ppt/immunpreg/> [20 September 2005]. Seppa, N. 2004 ââ¬ËSome T cells may be a fetusââ¬â¢ best friendââ¬â¢, Science News, [Online], vol. 165, no. 8, p125. Available from: Proquest. [11 October 2005]. Warshaw, J. (ed.) 1983, The Biological Basis of Reproductive and Developmental Medicine, Elsevier Science Publishing Co., New York.
Monday, January 20, 2020
James Arthur Baldwin :: Biography James Baldwin Writers Essays
James Arthur Baldwin James Arthur Baldwin was born the first of nine children during 1924 in Harlem. His father, David, was a clergyman and a factory worker, and was the source of all of James Baldwin's fears. Baldwin's mother, Berdis, was a homemaker. Baldwin first started writing around age fourteen as a way of seeking the love which he was missing from his family life. During this time Baldwin attended Frederick Douglas Junior High School and DeWitt Clinton High School. During his school years, Baldwin won several awards for his writings. The joy that he felt from having others praise his work was overshadowed, however, by his father's disapproval of his non-Christian-oriented writing. James Baldwin's father was a very religious Christian who forced the church on young James. For a few years (from ages fourteen through seventeen), Baldwin was even a preacher. It was the bittersweet beauty of the church which Baldwin said turned him into a writer. Those few years of lost herding opened James Baldwins' eyes to the fact that he was in need of soul searching. Those years would not be in vain; the cadences of black religious rituals sound throughout his writings. Baldwin was also known to credit his years at the pulpit for morphing him into the writer he was to become. In 1942 James Baldwin was fed up with his father, fed up with the church, and (at that point) fed up with his life. The brassy, young Baldwin went into a restaurant, which he knew was designated for whites only, and demanded that he be served. When the waitress informed him that they did not serve his "kind" in that restaurant Baldwin picked up a glass and hurled it at her with all his pent up spite for the world. (That was the last straw for James Baldwin, he knew that he needed to leave his home since childhood for new experiences, and did so that very same day.) With a high school diploma under his belt James Baldwin moved to New Jersey and began working as a railroad hand. After two years in New Jersey, Baldwin moved to Greenwich Village. There, he first met Richard Wright (an African-American author whose strong protests against racial prejudice made him one of his generation's most important spokespersons) and began his first novel, In My Father's House. It was not until four years later that James Baldwin began to receive recognition, such as awards and fellowships, for his writings.
Saturday, January 11, 2020
ââ¬ÅReview of AIDS and Stigmaââ¬â¢ by Gregory M. Harek
The current literature as of 1999 is reviewed regarding the stigma that attaches to people with AIDS (PWAââ¬â¢s and people with HIV (PWHIVs). à ââ¬Å"Stigmaâ⬠refers to discrimination and prejudice directed at PWAs and PWHIVs as well as those people associated with them or caregivers for them.This stigma has resulted in firings, evictions, and other forms of prejudice to people with AIDS and HIV. The existence of stigma has had a bad effect on the response to the AIDS crisis and could have a continuing affect on the various policies designed to assist PWAs and PWHIVs.Surveys throughout the world and specifically in the United States have indicated a negative attitude towards PWAs and PWHIVs by a significant majority of people.There are several possible reasons for the stigma. Many people believe PWAs and PWHIVs got the disease by their own actions and behavior. Others fear contracting the disease from any contact with PWAs and PWHIVs.Then there is the stigma associated wit h any disease considered that cannot be cured followed by the fear of contracting a contagious disease. Finally is the stigma associated with diseases or conditions affecting the victimsââ¬â¢ outward appearance and capability.The stigma of AIDS has an impact on a personal level and with society and public policy.à For example, many people with AIDS or HIV do not get tested for fear of the stigma attached to the disease.In society the negative attitude has and continues to have an effect on public policy and public health issues and legislation. However, the situation has changed over the years with education, and with continued education discrimination and prejudice towards PWAs and PWHIVs will further decrease.I like this article for several reasons. It is well written and organized. It is written in a style and manner which is easy to read for the average student.There is no specialized language or information presented. Additionally there are no graphs or tables of statisti cs or lengthy quotations or references to other work. There is no detectible bias in the article. It is a very relevant topic today as much as it was when written. It is very thought provoking and informative regarding a variety of issues.The issue of stigma can have a very strong affect on the individual reader, as it has had on me. Unfortunately AIDS has spread to the point where more and more people know of someone afflicted with the disease or know someone who has been directly affected by the disease.With this increase comes the awareness of the stigma associated with PWAs and PWHIV, and the likelihood that someone we know has suffered from discrimination or prejudice.There is an ââ¬Å"associationâ⬠effect as well, when there is a similar prejudice, discrimination or fear of people who take care of or are related to PWAs and PWHIVs. The information presented in the article cannot help but make the individual aware of the issue if he or she is not already familiar with the disease, and adds knowledge to those who are familiar with it.Additionally, it makes the individual, and me, question whether or not I harbor any prejudice or discrimination and if so how I exhibit it. This article is very good at making me look past myself to broader issues, as well as to look inside myself for attitudes I should question.I particularly like the method in which the causes of stigma are presented. It is particularly helpful in examining whether or not I believe in any of the reasons or use them as an excuse. It is also helpful in realizing the fallacy of many of the reasons.The first reason presented seems very irrelevant, as regardless of how someone contracted AIDS or any disease should have no bearing on attitude, although for many people religious belief may be a factor that cannot be easily ignored.The second reason, fear of contracting the disease, was a personal fear of mine until I became aware of the fact that it cannot be contracted by casual contact. Com mon sense tells us that we are probably around PWAs and PWHIVs daily without knowing it, and there has been no cases caused by casual contact.The third and fourth reasons are the ones that I have the most difficult time with, as I have always been uncomfortable around people with life-threatening or terminal diseases, or people who obviously show outward signs of the disease.I believe many people have this discomfort, and probably always will, as it can be very difficult to interact with such strong issues ââ¬Å"in the backgroundâ⬠. However, what is important is to keep the discomfort into becoming a prejudice or source of discrimination.I really liked the article because it is hopeful. It has taken a very difficult and depressing topic but presented it a manner which gives optimism to the issue. It does this by making the reader aware of the reasons, and on reflection, realizes all of the reasons can be lessened or removed with awareness and education.It has made me more awar e of a very significant issue in society today. It has also caused me to reflect on my personal attitude and actions. It has clearly presents a thesis and evidence in an easy-to-read manner.I like it because it stresses how common and damaging prejudice and discrimination is, and the role of education in overcoming prejudice, which is important not just for PWAs and PWHIVs but for everyone. Finally, it is an article I can use as reference to anyone who can benefit from the information or may be interested in the issue.Works CitedHarek, Gregory M. ââ¬Å"AIDS and Stigmaâ⬠. American Behavioral Scientist, Volume 42, No. 7, April 1999. 1102-1112.
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